重组锌指蛋白318
交货期:1周
产品别名:Recombinant ZNF318
Recombinant zinc finger protein 318 protein
基因名:
ZNF318
产品别名:
HRIHFB2436; TZF; ZFP318; ZNF318; zinc finger protein 318; zinc finger protein 318; zinc finger protein 318; endocrine regulator; endocrine regulatory protein; testicular zinc finger; 锌指蛋白318;
背景信息:
ZNF318 is a 2279 amino acid endocrine regulatory protein that localizes to the nucleus. Highly expressed in testis, ovaries and kidneys, ZNF318 is a co-repressor of androgen receptor (AR)-mediated transcriptional activation and is thought to regulate transcription during spermatogenesis. ZNF318 interacts with the N-terminal domain of AR and contains two matrin-type zinc fingers. Two isoforms of ZNF318, designated TZF and TZF-L, are produced due to alternative splicing events. Each of these splice variants are thought to have unique roles in transcriptional regulation. While the TZF isoform functions as a repressor of AR-mediated transcriptional activation, the TZF-L isoform is thought to enhance AR-mediated transcriptional activation.
产品发布日期:2025.05.16