重组囊泡乙酰胆碱转运蛋白(VAChT)
交货期：1周
产品别名：重组囊泡乙酰胆碱通道蛋白
Recombinant SLC18A3
Recombinant SLC18A3
基因名：
产品别名：
背景信息：
SLC18A3
产品别名：
CMS21； VACHT； SLC18A3； solute carrier family 18 member A3； solute carrier family 18 member A3； vesicular acetylcholine transporter； solute carrier family 18 (vesicular acetylcholine transporter), member 3； solute carrier family 18 (vesicular acetylcholine), member 3； solute carrier family 18, member 3； 囊泡乙酰胆碱转运蛋白(VAChT)； 囊泡乙酰胆碱通道；
背景信息：
Vesicular Acetylcholine Transporter (VAChT), (70kD protein), belongs to the family of vesicular monoamine transporters(VMATs), which include VMAT1 and VMAT2 and the C.elegans putative ACh transporter unc-17. Members of this family function to concentrate neurotransmitters into synaptic vesicles through exchange of protons for neurotransmitters. VAChT is a functional transporter for the neurotransmitter acetylcholine(ACh). ACh is synthesized in the cytoplasm by choline acetyl transferase (ChAT) and transported by VAChT into synaptic vesicles where it is stored until released. After release from presynaptic nerve terminals ACh is hydrolyzed by extracellular ACh-esterases(AChE) to choline and acetate.
VAChT mRNA is expressed in all known major cholinergic neurons in the central and peripheral nervous system. VAChT is abundantly expressed in the CNS and is mainly localized in small synaptic vesicles in cholinergic nerve terminals. VAChT provides a specific marker for cholinergic neurons for the study of cholinergic transmission in experimental models, in Alzheimer’s disease and other nervous system disorders.
VAChT mRNA is expressed in all known major cholinergic neurons in the central and peripheral nervous system. VAChT is abundantly expressed in the CNS and is mainly localized in small synaptic vesicles in cholinergic nerve terminals. VAChT provides a specific marker for cholinergic neurons for the study of cholinergic transmission in experimental models, in Alzheimer’s disease and other nervous system disorders.
产品发布日期：2025.05.16
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