磷酸二酯酶12(PDE12)抗体
交货期:1周
产品别名:Anti-PDE12
Anti-phosphodiesterase 12 Antibody
靶标:
PDE12
产品别名:
2'-PDE; 2-PDE; PDE12; phosphodiesterase 12; phosphodiesterase 12; 2',5'-phosphodiesterase 12; 2'-phosphodiesterase; mitochondrial deadenylase; 磷酸二酯酶12(PDE12);
背景信息:
Enzyme that cleaves 2',5'-phosphodiester bond linking adenosines of the 5'-triphosphorylated oligoadenylates, triphosphorylated oligoadenylates referred as 2-5A modulates the 2-5A system. Degrades triphosphorylated 2-5A to produce AMP and ATP. Also cleaves 3',5'-phosphodiester bond of oligoadenylates. Plays a role as a negative regulator of the 2-5A system that is one of the major pathways for antiviral and antitumor functions induced by interferons (IFNs. Suppression of this enzyme increases cellular 2-5A levels and decreases viral replication in cultured small-airway epithelial cells and Hela cells.
产品发布日期:2025.07.11