Dapper2蛋白抗体
交货期：1周
产品别名：Anti-DACT2
Anti-dishevelled binding antagonist of beta catenin 2 Antibody
Anti-dishevelled binding antagonist of beta catenin 2 Antibody
靶标：
产品别名：
背景信息：
DACT2
产品别名：
C6orf116； DAPPER2； DPR2； bA503C24.7； DACT2； dishevelled binding antagonist of beta catenin 2； dishevelled binding antagonist of beta catenin 2； dapper homolog 2； dapper antagonist of catenin 2； dapper homolog 2, antagonist of beta-catenin； dapper, antagonist of beta-catenin, homolog 2； Dapper2蛋白；
背景信息：
The Wnt signaling cascade is a conserved process in multicellular animals that plays important roles during development and can contribute to cancer and other diseases. Many members of this pathway are also expressed in the postnatal tissues such as brain. One such protein is Dact2, a member of the Dact protein family that was initially identified through binding to Disheveled (Dvl), a cytoplasmic protein essential to Wnt signaling. Dact2 is most prominent during the development of the thymus kidneys, and salivary gland. Dact2 is thought to play a role distinct from that of Dact1 with Dact2 having a greater impact on a beta-catenin-independent process termed planar cell polarity/convergent-extension signaling. Furthermore, Dact2 but not Dact1 can inhibit Nodal signaling by promoting the endocytic degradation of TGF-beta receptors. At least two isoforms of Dact2 are known to exist.
产品发布日期：2025.06.27
广州伟伯科技有限公司