磷脂酰肌醇PREX2抗体
交货期:1周
产品别名:Anti-PREX2
Anti-phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2 Antibody
靶标:
PREX2
产品别名:
DEP.2; DEPDC2; P-REX2; PPP1R129; PREX2; phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2; phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2; phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein; DEP domain-containing protein 2; PtdIns(3,4,5)-dependent Rac exchanger 2; protein phosphatase 1, regulatory subunit 129; 磷脂酰肌醇PREX2;
背景信息:
PREX2 functions as a RAC1 guanine nucleotide exchange factor (GEF), activating Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. PREX2 mediates the activation of RAC1 in a PI3K-dependent manner. PREX2 may be an important mediator of Rac signaling, acting directly downstream of both G protein-coupled receptors and phosphoinositide 3-kinase.
产品发布日期:2025.07.07