RHOT1抗体
交货期:1周
产品别名:Anti-RHOT1
Anti-ras homolog family member T1 Antibody
靶标:
RHOT1
产品别名:
ARHT1; MIRO-1; MIRO1; RHOT1; ras homolog family member T1; ras homolog family member T1; mitochondrial Rho GTPase 1; mitochondrial Rho (MIRO) GTPase 1; rac-GTP binding protein-like protein; ras homolog gene family, member T1;
背景信息:
Mitochondrial Rho GTPase 1 (MIRO1) is an enzyme that in humans is encoded by the RHOT1 gene on chromosome 17. The Ras homolog family member T1 (RHOT) is an atypical Rho Ca2+-binding GTPase that localizes to the mitochondria. RHOT1, the related protein RHOT2, the adaptor protein Milton, and the PTEN induced putative kinase 1 (PINK1), form a complex that is involved in axonal transport of mitochondria. Both PINK1 and Parkin target RHOT1 for phosphorylation and degradation, causing the arrest of mitochondrial motility.
产品发布日期:2025.07.01