NSMCE4A蛋白抗体
交货期：1周
产品别名：Anti-NSMCE4A
Anti-NSE4 homolog A, SMC5-SMC6 complex component Antibody
Anti-NSE4 homolog A, SMC5-SMC6 complex component Antibody
靶标：
产品别名：
背景信息：
NSMCE4A
产品别名：
C10orf86； NS4EA； NSE4A； NSMCE4A； NSE4 homolog A, SMC5-SMC6 complex component； NSE4 homolog A, SMC5-SMC6 complex component； non-structural maintenance of chromosomes element 4 homolog A； NSE4 homolog, SMC5-SMC6 complex component A； non-SMC element 4 homolog A； NSMCE4A蛋白；
背景信息：
NSMCE4A is a component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT-associated PML bodies (APBs). It is involved in positive regulation of response to DNA damage stimulus.
产品发布日期：2025.07.17
广州伟伯科技有限公司