Bruton酪氨酸激酶抑制剂蛋白抗体
交货期:1周
产品别名:Anti-IBTK
Anti-inhibitor of Bruton tyrosine kinase Antibody
靶标:
IBTK
产品别名:
BTBD26; BTKI; IBTK; inhibitor of Bruton tyrosine kinase; inhibitor of Bruton tyrosine kinase; inhibitor of Bruton tyrosine kinase; BTK-binding protein; Bruton agammaglobulinemia tyrosine kinase inhibitor; inhibitor of Bruton's tyrosine kinase-alpha; inhibitor of Bruton's tyrosine kinase-beta; inhibitor of Bruton's tyrosine kinase-gamma; Bruton酪氨酸激酶抑制剂蛋白;
背景信息:
Bruton tyrosine kinase (BTK) is a protein tyrosine kinase that is expressed in B cells, macrophages, and neutrophils. The protein encoded by this gene binds to BTK and downregulates BTK's kinase activity. In addition, the encoded protein disrupts BTK-mediated calcium mobilization and negatively regulates the activation of nuclear factor-kappa-B-driven transcription. This gene has a pseudogene on chromosome 18. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2014],
产品发布日期:2025.06.06