MAPKBP1抗体
交货期：1周
产品别名：Anti-MAPKBP1
Anti-mitogen-activated protein kinase binding protein 1 Antibody
Anti-mitogen-activated protein kinase binding protein 1 Antibody
靶标：
产品别名：
背景信息：
MAPKBP1
产品别名：
JNKBP-1； JNKBP1； NPHP20； MAPKBP1； mitogen-activated protein kinase binding protein 1； mitogen-activated protein kinase binding protein 1； mitogen-activated protein kinase-binding protein 1； JNK-binding protein 1；
背景信息：
This gene encodes a scaffold protein that regulates the JNK (c-Jun N-terminal kinase) and NOD2 (nucleotide-binding oligomerization domain-containing protein 2) signaling pathways. The encoded protein interacts with another related JNK pathway scaffold protein, WDR62, via a conserved dimerization domain, and enhances JNK signaling. This protein may play a role in bacterial immunity by binding to the NOD2 receptor and negatively regulating downstream antibacterial and pro-inflammatory signaling. Mutations in this gene that impair cellular localization of the encoded protein cause a form of nephronophthisis, an autosomal-recessive kidney disorder, in human patients.
产品发布日期：2025.07.24
广州伟伯科技有限公司