广州伟伯科技有限公司
SMG7抗体

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交货期:1周
产品别名:Anti-SMG7
Anti-SMG7 nonsense mediated mRNA decay factor Antibody
靶标:

SMG7


产品别名:

C1orf16; EST1C; SGA56M; SMG7; SMG7 nonsense mediated mRNA decay factor; SMG7 nonsense mediated mRNA decay factor; nonsense-mediated mRNA decay factor SMG7; EST1 telomerase component homolog C; EST1-like protein C; breast cancer-associated antigen SGA-56M; ever shorter telomeres 1C; smg-7 homolog, nonsense mediated mRNA decay factor;


背景信息:
SMG7, nonsense mediated mRNA decay factor(SMG7) Homo sapiens This gene encodes a protein that is essential for nonsense-mediated mRNA decay (NMD); a process whereby transcripts with premature termination codons are targeted for rapid degradation by a mRNA decay complex. The mRNA decay complex consists, in part, of this protein along with proteins SMG5 and UPF1. The N-terminal domain of this protein is thought to mediate its association with SMG5 or UPF1 while the C-terminal domain interacts with the mRNA decay complex. This protein may therefore couple changes in UPF1 phosphorylation state to the degradation of NMD-candidate transcripts. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Aug 2011],
产品发布日期:2025.06.30
广州伟伯科技有限公司