18号染色体开放阅读框1抗体
交货期：1周
产品别名：Anti-LDLRAD4
Anti-low density lipoprotein receptor class A domain containing 4 Antibody
Anti-low density lipoprotein receptor class A domain containing 4 Antibody
靶标：
产品别名：
背景信息：
LDLRAD4
产品别名：
C18orf1； LDLRAD4； low density lipoprotein receptor class A domain containing 4； low density lipoprotein receptor class A domain containing 4； low-density lipoprotein receptor class A domain-containing protein 4； clone 22； 18号染色体开放阅读框1；
背景信息：
Functions as a negative regulator of TGF-beta signaling and thereby probably plays a role in cell proliferation, differentiation, apoptosis, motility, extracellular matrix production and immunosuppression. In the canonical TGF-beta pathway, ZFYVE9 SARA recruits the intracellular signal transducer and transcriptional modulators SMAD2 and SMAD3 to the TGF-beta receptor. Phosphorylated by the receptor, SMAD2 and SMAD3 then form a heteromeric complex with SMAD4 that translocates to the nucleus to regulate transcription. Through interaction with SMAD2 and SMAD3, LDLRAD4 may compete with ZFYVE9 and SMAD4 and prevent propagation of the intracellular signal.
产品发布日期：2025.07.07
广州伟伯科技有限公司