重组砷酸盐耐药蛋白ARS2
交货期：1周
产品别名：Recombinant SRRT
Recombinant serrate, RNA effector molecule protein
Recombinant serrate, RNA effector molecule protein
基因名：
产品别名：
背景信息：
SRRT
产品别名：
ARS2； ASR2； serrate； SRRT； serrate, RNA effector molecule； serrate, RNA effector molecule； serrate RNA effector molecule homolog； arsenate resistance protein 2； arsenate resistance protein ARS2； arsenite resistance protein； arsenite-resistance protein 2； 砷酸盐耐药蛋白ARS2；
背景信息：
ARS2(Arsenite resistance protein 2) confers arsenite resistance. The protein belongs to the ARS2 family. Arsenic is a human carcinogen whose mechanism of action is unknown. The arsenite acts as a comutagen by interfering with DNA repair. Two genes, ASR1(Arsenite resistance protein 1) and ASR2 (Arsenite resistance protein 2), confer arsenite resistance to arsenite-sensitive cells. ASR1 shows almost complete homology with the rat fau gene, a tumor suppressor gene which contains a ubiquitin like region fused to S30 ribosomal protein. Arsenite inhibits ubiquitin dependent proteolysis. The tumor suppressor fau gene product or some other aspect of the ubiquitin system may be a target for arsenic toxicity and that disruption of the ubiquitin system may contribute to the genotoxicity and carcinogenicity of arsenite.
产品发布日期：2026.10.15
广州伟伯科技有限公司