重组剪接体相关蛋白62
交货期：1周
产品别名：Recombinant SF3A2
Recombinant splicing factor 3a subunit 2 protein
Recombinant splicing factor 3a subunit 2 protein
基因名：
产品别名：
背景信息：
SF3A2
产品别名：
PRP11； PRPF11； SAP62； SF3a66； SF3A2； splicing factor 3a subunit 2； splicing factor 3a subunit 2； splicing factor 3A subunit 2； SAP 62； pre-mRNA splicing factor SF3A, subunit 2； spliceosome associated protein 62； splicing factor 3a, subunit 2, 66kD； splicing factor 3a, subunit 2, 66kDa； 剪接体相关蛋白62；
背景信息：
SAP 62, also known as SF3A2 (Splicing factor 3A subunit 2), PRP11, PRPF11 or SF3a66, is a 464 amino acid protein that contains one matrin-type zinc finger and belongs to the SF3A2 family. Localized to the nucleus, SAP 62 is a subunit of the SF3A splicing factor, a heterotrimeric complex comprised of three subunits that act in tandem to mediate the binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. The SF3A complex is necessary for the conversion of 15S U2 snRNP into the active 17S protein that performs directly in pre-mRNA splicing events. Functioning as the second subunit of the complex, SAP 62 interacts with subunit 1 (SAP 114) via its N-terminus while simultaneously binding to 15S U2 snRNP via its zinc finger domain. In addition to its role in RNA splicing, SAP 62 is thought to act independently as a microtubule-binding protein.
产品发布日期：2026.10.15
广州伟伯科技有限公司