广州伟伯科技有限公司
14号染色体开放阅读框174抗体

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交货期:1周
产品别名:Anti-SAMD15
Anti-sterile alpha motif domain containing 15 Antibody
靶标:

SAMD15


产品别名:

C14orf174; FAM15A; SAMD15; sterile alpha motif domain containing 15; sterile alpha motif domain containing 15; sterile alpha motif domain-containing protein 15; SAM domain-containing protein 15; SAM domain-containing protein C14orf174; family with sequence similarity 15, member A; 14号染色体开放阅读框174;


背景信息:
C14orf174, is a 674 amino acid protein that contains one SAM (sterile alpha motif) domain. Existing as two alternatively spliced isoforms,C14orf174 is encoded by a gene that maps to human chromosome 14q24.3. Chromosome 14 contains about 700 genes and 106 million base pairs and makes up about 3.5% of human cellular DNA. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease. The SERPINA1 gene is located on chromosome 14 and when defective leads to the genetic disorder ?-antitrypsin deficiency. This disorder is characterized by severe lung complications and liver dysfunction. Notably, the immunoglobulin heavy chain locus is found on chromosome 14 and has been identified as a fusion with the chromosome 19 encoded protein Bcl-3 in the (14;19) translocations found in a variety of B cell malignancies.
产品发布日期:2026.04.15
广州伟伯科技有限公司