PACS1抗体
交货期:1周
产品别名:Anti-PACS1
Anti-phosphofurin acidic cluster sorting protein 1 Antibody
靶标:
PACS1
产品别名:
MRD17; SHMS; PACS1; phosphofurin acidic cluster sorting protein 1; phosphofurin acidic cluster sorting protein 1; phosphofurin acidic cluster sorting protein 1; PACS-1; cytosolic sorting protein PACS-1;
背景信息:
This gene encodes a protein with a putative role in the localization of trans-Golgi network (TGN) membrane proteins. Mouse and rat homologs have been identified and studies of the homologous rat protein indicate a role in directing TGN localization of furin by binding to the protease's phosphorylated cytosolic domain. In addition, the human protein plays a role in HIV-1 Nef-mediated downregulation of cell surface MHC-I molecules to the TGN, thereby enabling HIV-1 to escape immune surveillance. [provided by RefSeq, Jul 2008],
产品发布日期:2026.10.20