DPH5蛋白抗体
交货期:1周
产品别名:Anti-Dph5
Anti-Diphthamide methyltransferase Antibody
靶标:
Dph5
产品别名:
BcDNA.LD12153; BcDNA:LD12153; CG31289; CG5275; Dmel\CG31289; l(3)L4910; Dph5; Diphthamide methyltransferase; Diphthamide methyltransferase; diphthamide methyltransferase; CG31289-PA; Dph5-PA; DPH5蛋白;
背景信息:
Diphthine synthase is an enzyme that in humans is encoded by the DPH5 gene. This gene encodes a component of the diphthamide synthesis pathway. Diphthamide is a post-translationally modified histidine residue found only on translation elongation factor 2. It is conserved from archaebacteria to humans, and is targeted by diphtheria toxin and Pseudomonas exotoxin A to halt cellular protein synthesis. The yeast and Chinese hamster homologs of this protein catalyze the trimethylation of the histidine residue on elongation factor 2, resulting in a diphthine moiety that is subsequently amidated to yield diphthamide. Multiple transcript variants encoding different isoforms have been found for this gene.
产品发布日期:2026.04.15