少汗型外胚层发育不良相关蛋白EDAD抗体
交货期：1周
产品别名：Anti-EDARADD
Anti-EDAR associated death domain Antibody
Anti-EDAR associated death domain Antibody
靶标：
产品别名：
背景信息：
EDARADD
产品别名：
ECTD11A； ECTD11B； ED3； EDA3； EDARADD； EDAR associated death domain； EDAR associated death domain； ectodysplasin-A receptor-associated adapter protein； EDAR-associated death domain protein； crinkled homolog； ectodysplasia A receptor associated death domain； 少汗型外胚层发育不良相关蛋白EDAD；
背景信息：
This gene was identified by its association with ectodermal dysplasia, a genetic disorder characterized by defective development of hair, teeth, and eccrine sweat glands. The protein encoded by this gene is a death domain-containing protein, and is found to interact with EDAR, a death domain receptor known to be required for the development of hair, teeth and other ectodermal derivatives. This protein and EDAR are coexpressed in epithelial cells during the formation of hair follicles and teeth. Through its interaction with EDAR, this protein acts as an adaptor, and links the receptor to downstream signaling pathways. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
产品发布日期：2025.07.18
广州伟伯科技有限公司