DEPDC5抗体
交货期:1周
产品别名:Anti-DEPDC5
Anti-DEP domain containing 5, GATOR1 subcomplex subunit Antibody
靶标:
DEPDC5
产品别名:
DEP.5; FFEVF; FFEVF1; DEPDC5; DEP domain containing 5, GATOR1 subcomplex subunit; DEP domain containing 5, GATOR1 subcomplex subunit; GATOR complex protein DEPDC5; DEP domain-containing protein 5;
背景信息:
As a component of the GATOR1 complex functions as an inhibitor of the amino acid-sensing branch of the TORC1 pathway. The GATOR1 complex strongly increases GTP hydrolysis by RRAGA and RRAGB within RRAGC-containing heterodimers, thereby deactivating RRAGs, releasing mTORC1 from lysosomal surface and inhibiting mTORC1 signaling. The GATOR1 complex is negatively regulated by GATOR2 the other GATOR subcomplex in this amino acid-sensing branch of the TORC1 pathway.
产品发布日期:2025.07.18